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Proceedings Paper

Investigations on laser thermokeratoplasty
Author(s): Ralf Brinkmann; Norbert Koop; Gerit Droege; Ulf Grotehusmann; Andrea Huber; Reginald Birngruber
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Paper Abstract

Homogeneous deep intrastromal coagulations are thought to be optical for effective laser thermokeratoplasty. We therefore investigated the thermal effects created by two different flashlamp-pumped IR lasers (Er:glass and Cr:Tm:Ho:YAG) as well as two different application modalities (direct fiber contact and intrastromal focusing). The physical and thermal parameters of corneal tissue and the threshold temperatures for corneal collagen denaturation in different time domains were determined using a water bath and IR laser radiation. The temperature required to coagulate corneal tissue in the millisecond time regime was found to be above 100 degrees C. Based on these results a thermal model was developed to calculate temperature profiles and coagulation zones in space and time for different exposures situations. Model calculations show the possibility to induce deep stromal effects with a spatially nearly homogeneous temperature distribution within the application volume while minimizing adverse effects in the corneal endothelium.

Paper Details

Date Published: 15 February 1994
PDF: 11 pages
Proc. SPIE 2079, Laser Applications in Ophthalmology, (15 February 1994); doi: 10.1117/12.168730
Show Author Affiliations
Ralf Brinkmann, Medizinisches Laserzentrum Luebeck GmbH (Germany)
Norbert Koop, Medizinisches Laserzentrum Luebeck GmbH (Germany)
Gerit Droege, Medizinisches Laserzentrum Luebeck GmbH (Germany)
Ulf Grotehusmann, Medizinisches Laserzentrum Luebeck GmbH (Germany)
Andrea Huber, Medizinisches Laserzentrum Luebeck GmbH (Germany)
Reginald Birngruber, Medizinisches Laserzentrum Luebeck GmbH (Germany)

Published in SPIE Proceedings Vol. 2079:
Laser Applications in Ophthalmology
Shlomo Timor Melamed, Editor(s)

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