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Proceedings Paper

Dosimetry and light distribution systems for photodynamic therapy at the Norwegian Radium Hospital
Author(s): Helen Heyerdahl; Trond Warloe; Qian Peng; Katarina Svanberg M.D.; Johan Moan; Harald B. Steen; Lars Othar Svaasand; Karl-Erik Giercksky
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Paper Abstract

Photodynamic therapy has been used for treatment of malignant cutaneous lesions. Photosensitizer has been topically applied, 5-aminolevulinic acid, with light delivered at 630 nm. A study of response rate to varying light doses was performed, it might seem that light doses of 40 - 50 J/cm2 is sufficient for superficial lesions. For nodular lesions higher light doses are needed. Some patients with tumors in the gastrointestinal tract have been treated with systemic administration of 5-aminolevulinic acid and re-treated with Photofrin in case of unsatisfactory results. From the preliminary material available 5-aminolevulinic acid seems less promising as a photosensitizer for internal lesions compared to dermal lesions.

Paper Details

Date Published: 1 March 1994
PDF: 10 pages
Proc. SPIE 2078, Photodynamic Therapy of Cancer, (1 March 1994); doi: 10.1117/12.168711
Show Author Affiliations
Helen Heyerdahl, Norwegian Radium Hospital (Norway)
Trond Warloe, Norwegian Radium Hospital (Norway)
Qian Peng, Institute for Cancer Research (Norway)
Katarina Svanberg M.D., Lund Univ. Hospital (Sweden)
Johan Moan, Institute for Cancer Research (Norway)
Harald B. Steen, Institute for Cancer Research (Norway)
Lars Othar Svaasand, Univ. of Trondheim (Norway)
Karl-Erik Giercksky, Norwegian Radium Hospital (Norway)

Published in SPIE Proceedings Vol. 2078:
Photodynamic Therapy of Cancer
Giulio Jori; Johan Moan; Willem M. Star, Editor(s)

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