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Proceedings Paper

Evaluation of prostatic optical properties and tissue response to photodynamic therapy in a canine model
Author(s): Sugandh D. Shetty; Qun Chen; Daniel Schultz; Brian C. Wilson; Michael S. Patterson; Fred W. Hetzel; Joseph C. Cerny
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Paper Abstract

A new modality of interstitial therapy to treat prostate cancer using photodynamic principles has been studied in a canine model. The effect of interstitial application of monochromatic light from an argon pumped dye laser at 630 nm was studied in a canine model. No significant hyperthermia was seen during the treatment. A concentric zone around the treatment fiber was seen during the treatment. A concentric zone around the treatment fiber was seen in PDT treated dogs and the maximum size was 18 mm. The data suggests that PDT may be clinically applicable in achieving tissue necrosis using interstitial light application in a solid organ like prostate.

Paper Details

Date Published: 1 March 1994
PDF: 6 pages
Proc. SPIE 2078, Photodynamic Therapy of Cancer, (1 March 1994); doi: 10.1117/12.168682
Show Author Affiliations
Sugandh D. Shetty, Henry Ford Hospital (United States)
Qun Chen, Henry Ford Hospital (United States)
Daniel Schultz, Henry Ford Hospital (United States)
Brian C. Wilson, Hamilton Regional Cancer Ctr. (Canada)
Michael S. Patterson, Hamilton Regional Cancer Ctr. (Canada)
Fred W. Hetzel, Henry Ford Hospital (United States)
Joseph C. Cerny, Henry Ford Hospital (United States)

Published in SPIE Proceedings Vol. 2078:
Photodynamic Therapy of Cancer
Giulio Jori; Johan Moan; Willem M. Star, Editor(s)

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