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Proceedings Paper

Effects of oxidative stress on erythrocyte deformability and fragility
Author(s): Serdar Caglayan; Rainer Bayer
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Paper Abstract

Most methods established so far to estimate RBC deformability are hard to standardize and include high error of measurement. For our present investigation on the effects of oxygen (O2) and ozone (O3) on red blood cell (RBC) deformability we used the method of laser diffraction in a combination of image analysis. After exposing RBC to O2 and/or O3 mechanical fragility was investigated by filtration of the RBC suspensions (hematocrit 5%) through 3 micrometers pore filter under pressure of 200 mmHg. Fragility remained unchanged after oxygenation. Astonishingly O3 in concentration >= 7 (mu) g/ml improved mechanical fragility (decrease of hemolysis after mechanical stress).

Paper Details

Date Published: 1 February 1994
PDF: 8 pages
Proc. SPIE 2082, Quantification and Localization Using Diffuse Photons in a Highly Scattering Medium, (1 February 1994); doi: 10.1117/12.167463
Show Author Affiliations
Serdar Caglayan, Heinrich-Heine-Univ. (Germany)
Rainer Bayer, Heinrich-Heine-Univ. (Germany)


Published in SPIE Proceedings Vol. 2082:
Quantification and Localization Using Diffuse Photons in a Highly Scattering Medium
Britton Chance; David T. Delpy; Marco Ferrari; Martin J. C. van Gemert; Gerhard J. Mueller; Valery V. Tuchin, Editor(s)

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