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Proceedings Paper

Functional monitoring of tissues using frequency-domain laser light scattering
Author(s): Yurii P. Sinichkin; Alexander G. Bogoroditsky; Albert H. Mavlyutov; Gennady A. Smolyakov; Valery V. Tuchin; Ilya V. Yaroslavsky
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Paper Abstract

Determination of the optical parameters of tissues is a necessary element of laser medical diagnostics and therapy planning. In this work a mathematical model of the photon migration in tissues is considered in the assumption of the harmonic modulation of the incident laser light. The scattering coefficient and the photon's life time in virtually absorbed state can be calculated from the modulation coefficient and phase shift between incident and scattered light. Frequency-domain measurements were performed using two laser diodes (wavelengths 805 and 850 nm) as light-modulated sources and fiber-optic light guides for delivering the light to tissues surface and collecting the back scattering output. It is shown that measured difference in phase shift of scattered light intensity is proportional to difference in mean pathlength of photons at two wavelengths.

Paper Details

Date Published: 1 February 1994
PDF: 6 pages
Proc. SPIE 2082, Quantification and Localization Using Diffuse Photons in a Highly Scattering Medium, (1 February 1994); doi: 10.1117/12.167458
Show Author Affiliations
Yurii P. Sinichkin, Saratov State Univ. (Russia)
Alexander G. Bogoroditsky, Saratov State Univ. (Russia)
Albert H. Mavlyutov, Saratov State Univ. (Russia)
Gennady A. Smolyakov, Saratov State Univ. (Russia)
Valery V. Tuchin, Saratov State Univ. (Russia)
Ilya V. Yaroslavsky, Saratov State Univ. (Russia)

Published in SPIE Proceedings Vol. 2082:
Quantification and Localization Using Diffuse Photons in a Highly Scattering Medium
Britton Chance; David T. Delpy; Marco Ferrari; Martin J. C. van Gemert; Gerhard J. Mueller; Valery V. Tuchin, Editor(s)

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