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Proceedings Paper

Infrared spectra of joint fluids
Author(s): Hans H. Eysel; Henry H. Mantsch; Michael Jackson
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Paper Abstract

The present study demonstrates the application of infrared spectroscopy to the diagnosis of arthritic conditions by analysis of joint fluids. The detection of carbon dioxide clathrates, their origin and the nature of the host material is discussed. The analytical sensitivity of mid IR second derivative spectra is demonstrated with the detection of the local anaesthetic lidocaine in some of the samples. Linear discriminant analysis and hierarchical clustering are successfully used to classify the spectra according to their respective clinical diagnosis.

Paper Details

Date Published: 31 January 1994
PDF: 2 pages
Proc. SPIE 2089, 9th International Conference on Fourier Transform Spectroscopy, (31 January 1994); doi: 10.1117/12.166735
Show Author Affiliations
Hans H. Eysel, Institute for Biodiagnostics (Canada)
Henry H. Mantsch, National Research Council Canada (Canada)
Michael Jackson, National Research Council Canada (Canada)

Published in SPIE Proceedings Vol. 2089:
9th International Conference on Fourier Transform Spectroscopy
John E. Bertie; Hal Wieser, Editor(s)

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