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Proceedings Paper

Time-gated imaging with femtosecond transillumination optical coherence tomography
Author(s): Michael R. Hee; Joseph A. Izatt; Joseph M. Jacobson; Eric A. Swanson; James G. Fujimoto
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Paper Abstract

We describe a new technique called femtosecond transillumination optical coherence tomography which combines femtosecond pulses, coherent heterodyne detection, and fiber- optic confocal imaging to achieve time-gated and spatially resolved imaging through diffusive biological tissue. Images of absorbing objects embedded in scattering biological media are demonstrated by selecting either the earliest arriving unscattered ballistic component or the least scattered portion of the diffuse transmitted light. Time and spatially resolved analysis of photon migration through model scattering systems is used to establish fundamental limits for this class of time-gated and spatially resolved optical imaging techniques, and to evaluate their potential biomedical applications in early tumor diagnosis.

Paper Details

Date Published: 14 September 1993
PDF: 10 pages
Proc. SPIE 1888, Photon Migration and Imaging in Random Media and Tissues, (14 September 1993); doi: 10.1117/12.154664
Show Author Affiliations
Michael R. Hee, Massachusetts Institute of Technology (United States)
Joseph A. Izatt, Massachusetts Institute of Technology (United States)
Joseph M. Jacobson, Massachusetts Institute of Technology (United States)
Eric A. Swanson, Lincoln Lab./MIT (United States)
James G. Fujimoto, Massachusetts Institute of Technology (United States)


Published in SPIE Proceedings Vol. 1888:
Photon Migration and Imaging in Random Media and Tissues
Britton Chance; Robert R. Alfano, Editor(s)

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