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Proceedings Paper

Autofluorescence of normal and tumor mucosa of human colon: a comprehensive analysis
Author(s): Giovanni F. Bottiroli; Renato Marchesini; Anna Cleta Croce; Marco Dal Fante; Carolina Cuzzoni; Silvana Di Palma; Pasquale Spinelli
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Paper Abstract

Both 'in vivo' and 'ex vivo' spectrofluorometric studies of neoplastic and non-neoplastic mucosa of human colon have been carried out, in order to verify the potentials of tissue natural fluorescence as a possible parameter to distinguish normal from diseased tissues, Spectrofluorometric analysis performed at colonoscopy on patients affected by neoplasia, showed that adenocarcinoma, adenoma and non-neoplastic mucosa differ in the fluorescence emissions. The results have been interpreted according to the data obtained on cryostatic sections from biopsies by means of a microspectrofluorometric analysis carried out on each histological component.

Paper Details

Date Published: 27 August 1993
PDF: 8 pages
Proc. SPIE 1887, Physiological Imaging, Spectroscopy, and Early-Detection Diagnostic Methods, (27 August 1993); doi: 10.1117/12.151183
Show Author Affiliations
Giovanni F. Bottiroli, Univ. di Pavia (Italy)
Renato Marchesini, Istituto Nazionale per lo Studio e la Curo dei Tumori (Italy)
Anna Cleta Croce, Univ. di Pavia (Italy)
Marco Dal Fante, Istituto Nazionale per lo Studio e la Curo dei Tumori (Italy)
Carolina Cuzzoni, Univ. di Pavia (Italy)
Silvana Di Palma, Istituto Nazionale per lo Studio e la Curo dei Tumori (Italy)
Pasquale Spinelli, Istituto Nazionale per lo Studio e la Curo dei Tumori (Italy)


Published in SPIE Proceedings Vol. 1887:
Physiological Imaging, Spectroscopy, and Early-Detection Diagnostic Methods
Randall Locke Barbour; Mark J. Carvlin, Editor(s)

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