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Proceedings Paper

Structural and functional bases of laser-microvessels interaction
Author(s): Valentine I. Kozlov; Oleg Alexandrov Terman; Vitalij Builin; Natalia A. Lebedeva; Nickolai Samoilov
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Paper Abstract

Structural and functional microcirculatory changes in tissues and organs (muscles, liver, derma, epinephros, brain cortex) under various dosages and powers of laser irradiation in the red (633 nm) and near infrared (890 nm) spectrum regions have been studied in experiments and clinic. In case of nonsensitized tissues the `photoactivation' range of power densities and doses of laser irradiation has been established. We have identified a short-term reaction of microvessels and a long-term reaction (adaptation). The former consists of intensification of microcirculation and metabolism rise in parenchymatous cells; the latter is connected with neoangiogenesis acceleration. The intensification of the blood microcirculation includes a dilation of microvessels of all orders, an amplification of arteriolar vasomotions and an opening of `reserved' capillaries. Data on the structural reconstruction of myocytes and endotheliocytes have shown that the high differential parenchymatous cells and its membrane structures are sensitive to low energy laser irradiation and, on the other hand, under low energy laser irradiation there is an activation of synthetic processes in the cells. Thus, during the laser-tissue interaction in such complex system as human organism the microcirculation plays the key role among the other systems.

Paper Details

Date Published: 14 July 1993
PDF: 12 pages
Proc. SPIE 1883, Low-Energy Laser Effects on Biological Systems, (14 July 1993); doi: 10.1117/12.148021
Show Author Affiliations
Valentine I. Kozlov, Institute for Laser Medicine (Russia)
Oleg Alexandrov Terman, Institute for Laser Medicine (Russia)
Vitalij Builin, Institute for Laser Medicine (Russia)
Natalia A. Lebedeva, Institute for Laser Medicine (Russia)
Nickolai Samoilov, Institute for Laser Medicine (Russia)

Published in SPIE Proceedings Vol. 1883:
Low-Energy Laser Effects on Biological Systems
Michal Schwartz; Michael Belkin, Editor(s)

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