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Proceedings Paper

Noncontact laser penetrating keratoplasty: in-vivo comparative evaluation in rabbit and cat
Author(s): Jean-Marie A. Parel; William Q. Jeffers; Gabriel Simon; Patrick Hostyn; Jean-Marc Legeais; Francois Kuhne; Yoshiko Takesue; Hiroyuki Shimada; Elena Barraquer; Hanspeter Loertscher; M. Nowicky; Qiushi Ren; Izuru Nose
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Paper Abstract

With their inherent precision and avoidance of tissue deformation, non-contact laser trephines may minimize graft postoperative astigmatism. Laser-cut corneal button geometry surpassed handheld and equaled Hanna and Krumeich vacuum held trephines, without significant endothelium or wound healing differences for linear cuts between laser and metal blades. To compare the laser with metal trephines, we performed 8 mm diameter grafts on 12 rabbits and 12 cats. A new laser system, using an advanced pulsed HF laser coupled to a computer controlled optical delivery system and equipped for quasi-instantaneous simultaneous 8-point corneal marking (200 ns) for precise suture placement at the 5.5 to 10.5 mm diameter and rapid corneal trephination (approximately equals 6 sec), or a new disposable sterile vacuum-assisted Hessburg-Barron (HB) trephine was used in each procedure. Circumferential keratotomies were more accurately and more easily performed with the laser. No statistical differences were found in wound strength and healing. The laser produced a slightly lower astigmatism. These initial results suggest the safety of HF laser corneal marking-trephination and its potential for PK procedures in humans.

Paper Details

Date Published: 24 June 1993
PDF: 9 pages
Proc. SPIE 1877, Ophthalmic Technologies III, (24 June 1993); doi: 10.1117/12.147556
Show Author Affiliations
Jean-Marie A. Parel, Bascom Palmer Eye Institute/Univ. of Miami School of Medicine (United States)
Univ. de Paris (France)
Univ. of Miami College of Engineering (United States)
William Q. Jeffers, Helios Inc. (United States)
Gabriel Simon, Bascom Palmer Eye Institute/Univ. of Miami School of Medicine (United States)
Patrick Hostyn, Bascom Palmer Eye Institute/Univ. of Miami School of Medicine (United States)
Univ. de Bordeaux II (France)
Jean-Marc Legeais, Bascom Palmer Eye Institute/Univ. of Miami School of Medicine (United States)
Univ. de Paris (France)
Francois Kuhne, Bascom Palmer Eye Institute/Univ. of Miami School of Medicine (United States)
Univ. de Bordeaux II (France)
Yoshiko Takesue, Bascom Palmer Eye Institute/Univ. of Miami School of Medicine (United States)
Fukuoka Univ (Japan)
Hiroyuki Shimada, Nihon Univ. (Japan)
Elena Barraquer, Instituto Barraquer (Spain)
Hanspeter Loertscher, Bascom Palmer Eye Institute/Univ. of Miami School of Medicine (United States)
M. Nowicky, Helios Inc. (United States)
Qiushi Ren, Bascom Palmer Eye Institute/Univ. of Miami School of Medicine (United States)
Univ. of Miami College of Engineering (United States)
Izuru Nose, Bascom Palmer Eye Institute/Univ. of Miami School of Medicine (United States)


Published in SPIE Proceedings Vol. 1877:
Ophthalmic Technologies III
Jean-Marie A. Parel; Qiushi Ren, Editor(s)

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