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Proceedings Paper

Comparison of laser-assisted fibrinogen bonding to sutured closure of umbilical vein graft
Author(s): Mehmet Cengiz Oz; John E. Souza; Matthew R. Williams; Herbert Dardik; Lawrence S. Bass; Michael R. Treat; Roman Nowygrod
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Paper Abstract

Despite success with autologous tissue welding, laser welding of synthetic vascular prostheses has not been possible. The graft material appears inert and fails to allow the collagen breakdown and electrostatic bonding which results in tissue welding. In order to develop a laser welding system for graft material, we repaired gluataldehyde-tanned human umbilical cord vein graft incisions using laser-assisted fibrinogen bonding (LAFB) technology. Modified umbilical vein graft was incised transversely (1.2 cm). Incisions were repaired using sutures, laser energy alone, or LAFB. In vivo evaluation of umbilical graft bonding with canine arteries demonstrates that LAFB can reliably reinforce sutured anastomoses. The described system for bonding graft material with laser exposed fibrinogen may allow creation or reinforcement of vascular anastomoses in procedures where use of autologous tissue is not feasible.

Paper Details

Date Published: 1 July 1993
PDF: 5 pages
Proc. SPIE 1876, Lasers in Otolaryngology, Dermatology, and Tissue Welding, (1 July 1993); doi: 10.1117/12.147024
Show Author Affiliations
Mehmet Cengiz Oz, Columbia Univ. College of Physicians and Surgeons (United States)
John E. Souza, Columbia Univ. College of Physicians and Surgeons (United States)
Matthew R. Williams, Columbia Univ. College of Physicians and Surgeons (United States)
Herbert Dardik, Englewood Hospital (United States)
Lawrence S. Bass, Columbia Univ. College of Physicians and Surgeons (United States)
Michael R. Treat, Columbia Univ. College of Physicians and Surgeons (United States)
Roman Nowygrod, Columbia Univ. College of Physicians and Surgeons (United States)


Published in SPIE Proceedings Vol. 1876:
Lasers in Otolaryngology, Dermatology, and Tissue Welding
R. Rox Anderson; Lawrence S. Bass; Stanley M. Shapshay; John V. White; Rodney A. White, Editor(s)

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