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Proceedings Paper

Photodynamic therapy of port wine stain: preliminary clinical studies
Author(s): J. Stuart Nelson
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Paper Abstract

The broad, long term objective of this work is the development of Photodynamic Therapy (PDT) for application in the clinical management of patients with port wine stain (PWS). PDT involves the use of an exogenous drug which is concentrated in a targeted tissue. When irradiated at wavelengths specifically absorbed by the drug, selective destruction of the targeted tissue, without the production of heat, occurs. The results of this preliminary study demonstrate in human PWS patients that a photosensitizer, such as PHOTOFRINR, activated by red light at the appropriate therapeutic wavelength, can cause destruction of subsurface blood vessels in the skin with a high degree of specificity, and further study appears warranted.

Paper Details

Date Published: 1 July 1993
PDF: 5 pages
Proc. SPIE 1876, Lasers in Otolaryngology, Dermatology, and Tissue Welding, (1 July 1993); doi: 10.1117/12.147022
Show Author Affiliations
J. Stuart Nelson, Univ. of California/Irvine (United States)


Published in SPIE Proceedings Vol. 1876:
Lasers in Otolaryngology, Dermatology, and Tissue Welding
R. Rox Anderson; Lawrence S. Bass; Stanley M. Shapshay; John V. White; Rodney A. White, Editor(s)

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