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Proceedings Paper

Imaging-guided interstitial tumor therapy for treatment of recurrent head and neck carcinomas: clinical experience
Author(s): Dan J. Castro; Keith E. Blackwell; Romaine E. Saxton; Antony Nyerges; Tom C. Calcaterra; Vicky L. Schiller; Edward G. Grant; Sharon Hirschowitz; Gary R. Duckwiler; Randall A. Hawkins
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Paper Abstract

Interstitial laser phototherapy (ILP) is a technique whereby laser energy is directly applied into tumors at variable depths. This technique is attractive since it is minimally invasive and carries a low morbidity. ILP allows treatment of deep and difficult to reach tumors in the head and neck and other areas, since sensitive and non-invasive monitoring techniques of laser-tissue interactions are currently available. Recent studies have demonstrated, the efficiency of ultrasound (UTZ) and magnetic resonance imaging (MRI) for real time interstitial needle placement in tumors, identification of vessels, monitoring and quantifying laser-induced tissue damages. We now report an initial experience with patients in which MRI and/or UTZ guided ILP techniques were successfully applied for the treatment of recurrent, nonresectable, metastatic squamous cell carcinoma.

Paper Details

Date Published: 1 July 1993
PDF: 18 pages
Proc. SPIE 1876, Lasers in Otolaryngology, Dermatology, and Tissue Welding, (1 July 1993); doi: 10.1117/12.147008
Show Author Affiliations
Dan J. Castro, UCLA School of Medicine (United States)
Keith E. Blackwell, UCLA School of Medicine (United States)
Romaine E. Saxton, UCLA School of Medicine (United States)
Antony Nyerges, UCLA School of Medicine (United States)
Tom C. Calcaterra, UCLA School of Medicine (United States)
Vicky L. Schiller, UCLA School of Medicine (United States)
Edward G. Grant, UCLA School of Medicine (United States)
Sharon Hirschowitz, UCLA School of Medicine (United States)
Gary R. Duckwiler, UCLA School of Medicine (United States)
Randall A. Hawkins, UCLA School of Medicine (United States)


Published in SPIE Proceedings Vol. 1876:
Lasers in Otolaryngology, Dermatology, and Tissue Welding
R. Rox Anderson; Lawrence S. Bass; Stanley M. Shapshay; John V. White; Rodney A. White, Editor(s)

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