Share Email Print

Proceedings Paper

Assessment of coronary vasomotion by intracoronary ultrasound
Author(s): Patrick J. Dupouy; Jean Luc Dubois-Rande; Gabriel Pelle; Dominique Gallot; Herbert J. Geschwind
Format Member Price Non-Member Price
PDF $14.40 $18.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

Recently, new intravascular ultrasound devices for intracoronary use became available. The aim of the study was to evaluate the accuracy of intravascular ultrasound for the assessment of coronary artery vasomotion and endothelial function in patients with atherosclerosis. Twenty patients with luminal irregularities on coronary angiogram and a high cholesterol level (287 +/- 19 mg/dl) (group 1) and 6 patients with angiographically smooth arteries and a minimally elevated cholesterol level (197 +/- 12 mg/dl) (group 2) were studied. A mechanical intravascular ultrasound probe (4.3 French, 30 MHz, Cardiovascular Imaging Systems) was placed into the proximal segment of the coronary artery. Off-line measurements of the lumen area and calculation of mean intimal thickness indice was performed using digitized ultrasound images. Endothelial function was studied during a sympathetic stimulation by a cold pressor test and after intracoronary administration of papaverine and linsidomine. Mean intimal thickness was higher in group 1 than in group 2 (1.52 +/- 0.64 mm vs. 0.18 +/- 0.08 mm, p < 0.001). Linsidomine infusion induced a significant vasodilating effect in both groups (p < 0.001).

Paper Details

Date Published: 23 June 1993
PDF: 6 pages
Proc. SPIE 1878, Diagnostic and Therapeutic Cardiovascular Interventions III, (23 June 1993); doi: 10.1117/12.146570
Show Author Affiliations
Patrick J. Dupouy, Univ. Hopital Henri Mondor (France)
Jean Luc Dubois-Rande, Univ. Hopital Henri Mondor (France)
Gabriel Pelle, Univ. Hopital Henri Mondor (France)
Dominique Gallot, Univ. Hopital Henri Mondor (France)
Herbert J. Geschwind, Univ. Hopital Henri Mondor (France)

Published in SPIE Proceedings Vol. 1878:
Diagnostic and Therapeutic Cardiovascular Interventions III
George S. Abela, Editor(s)

© SPIE. Terms of Use
Back to Top