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Proceedings Paper

Chirality of the local supercoiling of individual DNA molecules assigned by atomic force microscopy
Author(s): Bruno Samori; Giuliano Siligardi; Carla Quagliarello; Albrecht L. Weisenhorn; James Vesenka; Carlos J. Bustamante
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Paper Abstract

Reproducible images of pBR322 plasmid molecules have been recorded by Atomic Force Microscopy (AFM) under n-propanol. By applying a stratigraphic analysis which takes advantage of the height information contained in the AFM images, it is possible to assign the chirality of the local supercoiling of the individual molecules.

Paper Details

Date Published: 4 June 1993
PDF: 5 pages
Proc. SPIE 1855, Scanning Probe Microscopies II, (4 June 1993); doi: 10.1117/12.146374
Show Author Affiliations
Bruno Samori, Univ. della Calabria (Italy)
Giuliano Siligardi, Univ. della Calabria (Italy)
Carla Quagliarello, Univ. della Calabria (Italy)
Albrecht L. Weisenhorn, Univ. de Fribourg (Switzerland)
James Vesenka, Univ. of Oregon (United States)
Carlos J. Bustamante, Univ. of Oregon (United States)


Published in SPIE Proceedings Vol. 1855:
Scanning Probe Microscopies II
Clayton C. Williams, Editor(s)

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