Share Email Print
cover

Proceedings Paper

Light-emitting diode source for photodynamic therapy
Author(s): A. Charles Lytle; Brian K. Dalton; Daniel R. Doiron; Rick W. Keck; Steven H. Selman; Miriam E. Wagoner
Format Member Price Non-Member Price
PDF $14.40 $18.00

Paper Abstract

Lasers have traditionally been the preferred light source for activation of the photosensitizing agents used in photodynamic therapy (PDT). Their monochromaticity, high power, and the ability to couple that high power into optical fibers have dictated their use. There are however, many potential applications for PDT which do not require fiberoptic light delivery, and thus, need not incur the high cost associated with the use of laser systems. Treatment of skin cancer, cervical cancer, and cancers in the oral cavity could be effectively treated with alternative light sources, which would greatly reduce the cost of treatment. This paper will describe the features of a preclinical light emitting diode (LED) based source for photodynamic therapy, designed and built by PDT Systems. The results of an animal study, using the photosensitizer SnET2 activated at 660 nm, which compared the efficacy of PDT performed with a dye laser system with that of the LED system will be presented. Future plans for a clinical version of the LED system will also be discussed.

Paper Details

Date Published: 18 June 1993
PDF: 9 pages
Proc. SPIE 1881, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy II, (18 June 1993); doi: 10.1117/12.146308
Show Author Affiliations
A. Charles Lytle, PDT Systems (United States)
Brian K. Dalton, PDT Systems (United States)
Daniel R. Doiron, PDT Systems (United States)
Rick W. Keck, Medical College of Ohio (United States)
Steven H. Selman, Medical College of Ohio (United States)
Miriam E. Wagoner, Medical College of Ohio (United States)


Published in SPIE Proceedings Vol. 1881:
Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy II
Thomas J. Dougherty, Editor(s)

© SPIE. Terms of Use
Back to Top