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Proceedings Paper

Determination of optimal parameters for argon-laser-assisted carotid anastomoses in rats: macroscopic, thermal, and histological evaluation
Author(s): Veronique L. Martinot; Serge R. Mordon; Valerie A. Mitchell; P. N. Pellerin; Jean Marc Brunetaud
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Paper Abstract

The aim of this study was to determine the optimal parameters for an Argon laser (spot diameter equals 200 micrometers ) to obtain and reproduce vessel anastomoses. It was performed in 2 groups of Wistar rats. In the first group (89 shots on 10 carotids), the fluence was continuously adjusted from 30 to 3,000 J/cm2 in order to determine an optimal set of parameters (power from 90 to 200 mW, shot duration from 0.1 to 5 seconds, pulsed or continuous mode). In the second group, thirty end-to-end carotid anastomoses were evaluated by macroscopic, thermal and histological studies. The second group proved the efficiency of the selected parameters. Vessel welding was obtained with 100 mW, 3 seconds, continuous mode (fluence equals 950 J/cm2, irradiance equals 320 W/cm2) for a mean temperature of 77 degree(s)C corresponding to collagen denaturation. In the second group the patency rate was 93% (28/30) with 3 pseudo-aneurisms and 2 thromboses. Histological studies noted slight modifications of the media.

Paper Details

Date Published: 28 May 1993
PDF: 8 pages
Proc. SPIE 1879, Lasers in Urology, Gynecology, and General Surgery, (28 May 1993); doi: 10.1117/12.146237
Show Author Affiliations
Veronique L. Martinot, Service de Chirurgie (France)
Serge R. Mordon, INSERM (France)
Valerie A. Mitchell, INSERM U156 (France)
P. N. Pellerin, Service de Chirurgie (France)
Jean Marc Brunetaud, Lab. des Lasers (France)


Published in SPIE Proceedings Vol. 1879:
Lasers in Urology, Gynecology, and General Surgery
Christopher J. Daly; Warren S. Grundfest; Douglas E. Johnson; Raymond J. Lanzafame; Rudolf W. Steiner; Yona Tadir; Graham M. Watson, Editor(s)

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