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Proceedings Paper

Biphotonic reactions of a dihydropyridine derivative of AZT related to AIDS dementia
Author(s): L. Lindqvist; B. Czochralska; W. Kawczynski
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Paper Abstract

It was shown that exposure of the AZT derivative 5'-(1,4-dihydro-1-methyl-3- pyridinyl-carbonyl)-3'-azido-2', 3'-dideoxythymidine) (H2PyrAZT) in aqueous solution to pulsed laser emission ((lambda) equals 355 nm, pulse length 2 ns) gives rise to photoelectron ejection by stepwise two-photon absorption. Absorption spectra of the semioxidized radicals obtained in this reaction were determined. It was shown that the photolysis did not affect the azido group.

Paper Details

Date Published: 17 June 1993
PDF: 4 pages
Proc. SPIE 1922, Laser Study of Macroscopic Biosystems, (17 June 1993); doi: 10.1117/12.146200
Show Author Affiliations
L. Lindqvist, Univ. de Paris-Sud (France)
B. Czochralska, Univ. of Warsaw (Poland)
W. Kawczynski, Univ. of Warsaw (Poland)


Published in SPIE Proceedings Vol. 1922:
Laser Study of Macroscopic Biosystems

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