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Proceedings Paper

Bactericidal effect of YAG laser irradiation sensitized by chlorin e6
Author(s): Andrei Fomichev; I. Krylov; A. Degtyareva; Vladimir P. Zorin; Victor P. Mikhailov; I. Manichev; S. N. Charankevich
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Paper Abstract

The photoinduced damage sensitized by chlorin e6 to obligate-pathogenic bacteria Klebsiella rhinoscleromatis in the presence of streptomycin has been studied. A significant synergic effect is observed resulting in both higher photoinactivation rates in the presence of streptomycin and reduction of the threshold of toxic antibiotic concentrations for bacteria, exposed to the sublethal photosensitized action. One may expect that the use of the combined action of a photosensitizer and visible light will allow one to decrease an effective antibiotic dose using combined photo- and chemotherapy of scleroma.

Paper Details

Date Published: 17 June 1993
PDF: 7 pages
Proc. SPIE 1922, Laser Study of Macroscopic Biosystems, (17 June 1993); doi: 10.1117/12.146199
Show Author Affiliations
Andrei Fomichev, Belarussian State Univ. (Belarus)
I. Krylov, Belarussian State Univ. (Belarus)
A. Degtyareva, Belarussian State Univ. (Belarus)
Vladimir P. Zorin, Belarussian State Univ. (Belarus)
Victor P. Mikhailov, Belarussian State Univ. (Belarus)
I. Manichev, Belarussian State Univ. (Belarus)
S. N. Charankevich, Belarussian State Univ. (Belarus)

Published in SPIE Proceedings Vol. 1922:
Laser Study of Macroscopic Biosystems

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