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Proceedings Paper

Raman microspectroscopy and atomic force microscopy of chromosomal banding patterns
Author(s): Gerwin J. Puppels; Constant A.J. Putman; Bart G. de Grooth; Jan Greve
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Paper Abstract

The potentials and first results of a combined Raman microspectroscopic and atomic force microscopic study of the banding pattern of polytene chromosomes are described. The results of Raman experiments indicate that differences in DNA content between bands and interbands are not as large as previously suggested in the literature. By means of atomic force microscopy the ultrastructure of chromosome bands and interbands can be analyzed.

Paper Details

Date Published: 17 June 1993
PDF: 11 pages
Proc. SPIE 1922, Laser Study of Macroscopic Biosystems, (17 June 1993); doi: 10.1117/12.146192
Show Author Affiliations
Gerwin J. Puppels, Univ. of Twente (Netherlands)
Constant A.J. Putman, Univ. of Twente (Netherlands)
Bart G. de Grooth, Univ. of Twente (Netherlands)
Jan Greve, Univ. of Twente (Netherlands)

Published in SPIE Proceedings Vol. 1922:
Laser Study of Macroscopic Biosystems
Jouko E. Korppi-Tommola, Editor(s)

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