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Proceedings Paper

Molecular dynamics simulation of cytidine: 2'-deoxycytidine and their phosphate salts in a water solution
Author(s): K. Kulinska; A. Laaksonen
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Paper Abstract

To provide an insight how this only one more (or less) hydration site influences the pattern of hydration of this nucleic acid building blocks, computer simulation studies have been undertaken. The objectives of the molecular dynamics (MD) simulation studies of Cyd, dCyd and their phosphate salts in aqueous solutions were: 1. to compare the hydration pattern of the studied compounds in the ribo and deoxyribo series at the level of microscopic interactions, 2. to study intermolecular interactions in these molecular systems, 3. to explain the unexpectedly big difference in solubiity between the studied compounds in the ribo and deoxyribo series.

Paper Details

Date Published: 17 June 1993
PDF: 5 pages
Proc. SPIE 1921, Laser Spectroscopy of Biomolecules, (17 June 1993); doi: 10.1117/12.146147
Show Author Affiliations
K. Kulinska, Institute of Bioorganic Chemistry (Poland)
Univ. of Stockholm (Sweden)
A. Laaksonen, Univ. of Stockholm (Sweden)

Published in SPIE Proceedings Vol. 1921:
Laser Spectroscopy of Biomolecules
Jouko E. Korppi-Tommola, Editor(s)

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