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Proceedings Paper

Vibrational circular dichroism in molecules of pharmaceutical interest
Author(s): Teresa B. Freedman; Denise M. Gigante; Mario J. Citra; M. Germana Paterlini
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Paper Abstract

Vibrational circular dichroism (VCD) spectra provide information on the solution conformations of chiral molecules. The CH-, OH-, NH-, and C equals O-stretching VCD features are particularly useful conformational probes. Molecules of pharmaceutical interest studied by VCD include biomimetic iron carriers, unsaturated peptides, the anticancer drug taxol and a series of type I antiarrhythmic drugs.

Paper Details

Date Published: 1 May 1993
PDF: 7 pages
Proc. SPIE 1890, Biomolecular Spectroscopy III, (1 May 1993); doi: 10.1117/12.145258
Show Author Affiliations
Teresa B. Freedman, Syracuse Univ. (United States)
Denise M. Gigante, Syracuse Univ. (United States)
Mario J. Citra, Syracuse Univ. (United States)
M. Germana Paterlini, Syracuse Univ. (United States)

Published in SPIE Proceedings Vol. 1890:
Biomolecular Spectroscopy III
Laurence A. Nafie; Henry H. Mantsch, Editor(s)

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