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Proceedings Paper

Characterization of a sol-gel-entrapped artificial receptor
Author(s): Richard A. Dunbar; Upvan Narang; Paras N. Prasad; Frank V. Bright
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Paper Abstract

We report on the development, characterization, and photophysics of a new fiber-optic-based sensor which uses a sol-gel entrapped recognition element. The recognition element is modified (beta) -cyclodextrin to which we have added a short tether (glycine) and a fluorophore (dansyl). This recognition element forms an intramolecular complex, and the dansyl group can include within the cyclodextrin cavity. Non-fluorescent analytes, that bind to the cyclodextrin cavity, can effectively displace the included dansyl group and result in a measurable change in signal. We report on the detection limits, dynamic range, and photophysics (i.e., transduction mechanism) of this new sensor.

Paper Details

Date Published: 30 April 1993
PDF: 9 pages
Proc. SPIE 1796, Chemical, Biochemical, and Environmental Fiber Sensors IV, (30 April 1993); doi: 10.1117/12.143523
Show Author Affiliations
Richard A. Dunbar, SUNY/Buffalo (United States)
Upvan Narang, SUNY/Buffalo (United States)
Paras N. Prasad, SUNY/Buffalo (United States)
Frank V. Bright, SUNY/Buffalo (United States)


Published in SPIE Proceedings Vol. 1796:
Chemical, Biochemical, and Environmental Fiber Sensors IV
Robert A. Lieberman, Editor(s)

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