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Proceedings Paper

Laser-based fiberoptic immunosensors
Author(s): Tuan Vo-Dinh; Jean Pierre Alarie; Michael J. Sepaniak
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Paper Abstract

This paper provides a brief overview of the development and application of fiber-optic antibody-based fluoroimmunosensors (FIS) for measuring environmental pollutants and related biomarkers of human exposure and health effects. The FIS combines the excellent specificity of the antigen/antibody reaction, the high sensitivity of laser excitation, and the versatility of fiber-optics technology. Various types of FIS devices were also used to detect toxic chemicals (such as benzo-a-pyrene) and related DNA adducts (e.g., benzo(a)pyrene tetrol).

Paper Details

Date Published: 9 March 1993
PDF: 7 pages
Proc. SPIE 1716, International Conference on Monitoring of Toxic Chemicals and Biomarkers, (9 March 1993); doi: 10.1117/12.140280
Show Author Affiliations
Tuan Vo-Dinh, Oak Ridge National Lab. (United States)
Jean Pierre Alarie, Oak Ridge National Lab. (United States)
Michael J. Sepaniak, Univ. of Tennessee (United States)

Published in SPIE Proceedings Vol. 1716:
International Conference on Monitoring of Toxic Chemicals and Biomarkers
Tuan Vo-Dinh; Karl Cammann, Editor(s)

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