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Proceedings Paper

Spectroscopy in pharmaceutical development: an overview
Author(s): Stephen Scypinski; Ramaswamy Murari; Anne Grant; Sammy Ng
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Paper Abstract

Spectroscopic techniques play a key role in the everyday work of the pharmaceutical analyst. In addition to the normal use of the various spectroscopies for simple, routine analyses, a pharmaceutical analytical chemist might use spectroscopy to perform a host of additional functions. These might include, for example, the characterization of a polymorphic substance by either X-ray diffraction or nuclear magnetic resonance spectroscopy, the identification of a foreign material in a tablet dosage form by infrared microspectroscopy, or the selection of a wavelength for liquid chromatographic analysis by photodiode array ultraviolet-visible spectroscopy. The following presentation is meant to acquaint the non-pharmaceutical chemist with some of the ways spectroscopy is utilized in the pharmaceutical analysis research and development laboratory.

Paper Details

Date Published: 14 August 1992
PDF: 12 pages
Proc. SPIE 1681, Optically Based Methods for Process Analysis, (14 August 1992); doi: 10.1117/12.137725
Show Author Affiliations
Stephen Scypinski, Hoffmann-La Roche Inc. (United States)
Ramaswamy Murari, Hoffmann-La Roche Inc. (United States)
Anne Grant, Hoffmann-La Roche Inc. (United States)
Sammy Ng, Hoffmann-La Roche Inc. (United States)

Published in SPIE Proceedings Vol. 1681:
Optically Based Methods for Process Analysis
David S. Bomse; Harry Brittain; Stuart Farquharson; Jeremy M. Lerner; Alan J. Rein; Cary Sohl; Terry R. Todd; Lois Weyer, Editor(s)

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