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Proceedings Paper

Autologous bone marrow transplantation by photodynamic therapy
Author(s): Kirpal S. Gulliya
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Paper Abstract

Simultaneous exposure of Merocyanine 540 dye containing cultured tumor cells to 514-nm laser light (93.6 J/cm2) results in virtually complete cell destruction. Under identical conditions, 40% of the normal progenitor (CFU-GM) cells survive the treatment. Laser- photoradiation treated, cultured breast cancer cells also were killed, and living tumor cells could not be detected by clonogenic assays or by anti-cytokeratin monoclonal antibody method. Thus, laser photoradiation therapy could be useful for purging of contaminating tumor cells from autologous bone marrow.

Paper Details

Date Published: 1 June 1992
PDF: 4 pages
Proc. SPIE 1650, Medical Lasers and Systems, (1 June 1992); doi: 10.1117/12.137505
Show Author Affiliations
Kirpal S. Gulliya, Baylor Univ. Medical Ctr. (United States)


Published in SPIE Proceedings Vol. 1650:
Medical Lasers and Systems
David M. Harris; Stuart D. Harman, Editor(s)

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