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Proceedings Paper

Improvements in the accuracy and statistical variance of the Monte Carlo simulation of light distribution in tissue
Author(s): Craig M. Gardner; Ashley J. Welch
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Paper Abstract

Monte Carlo simulations provide accurate descriptions of light distribution in complex geometry, multiple layer tissues at the expense of long computation times. In addition, the accuracy of the light distribution quantity calculated is influenced by the resolution of the simulation if spatial convolution is used. A method of increasing the accuracy of the calculated fluence rate without increasing computation time is to consider the Beer-Lambert law source attenuation in the tissue analytically, separate from the Monte Carlo numeric calculation of the remaining multiple scattering process. A method of reducing the time of computation needed for a desired maximum statistical variance is to use a non-linear grid that provides high resolution in areas of interest and lower resolution far away from the source and boundaries. The theory of the source attenuation function is discussed. Results demonstrating the validity of the analytic function and the use of non-linear grids are provided and compared to standard Monte Carlo techniques.

Paper Details

Date Published: 7 August 1992
PDF: 10 pages
Proc. SPIE 1646, Laser-Tissue Interaction III, (7 August 1992); doi: 10.1117/12.137485
Show Author Affiliations
Craig M. Gardner, Univ. of Texas/Austin (United States)
Ashley J. Welch, Univ. of Texas/Austin (United States)


Published in SPIE Proceedings Vol. 1646:
Laser-Tissue Interaction III
Steven L. Jacques, Editor(s)

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