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Proceedings Paper

Effects of additives on laser-assisted fibrinogen bonding
Author(s): G. Michael Lemole; Robert C. Ashton; Mehmet Cengiz Oz; I. Arikan; D. Arikan; Gerald M. Lemole
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Paper Abstract

In order to produce a solder for Laser-Assisted Tissue Bonding (LATB) with better tactile characteristics and shelf life, plasma-derived fibrinogen concentrate has been augmented with various additives, including anionic polysaccharides, anti-fibrinolytic agents, and preservatives. For comparison of this new, compounded 'solder' with the pure, plasma- derived fibrinogen concentrate an in vivo tissue 'weld' assay was devised. While further analyses must be done to assess more critical healing time periods and characteristics, this study is an affirmation that the plasma-derived, protein concentrates, with or without certain additives, offer effective alternatives to suture repair.

Paper Details

Date Published: 1 June 1992
PDF: 4 pages
Proc. SPIE 1643, Laser Surgery: Advanced Characterization, Therapeutics, and Systems III, (1 June 1992); doi: 10.1117/12.137352
Show Author Affiliations
G. Michael Lemole, Medical Ctr. of Delaware (United States)
Robert C. Ashton, Medical Ctr. of Delaware (United States)
Mehmet Cengiz Oz, Medical Ctr. of Delaware (United States)
I. Arikan, Medical Ctr. of Delaware (United States)
D. Arikan, Medical Ctr. of Delaware (United States)
Gerald M. Lemole, Medical Ctr. of Delaware (United States)


Published in SPIE Proceedings Vol. 1643:
Laser Surgery: Advanced Characterization, Therapeutics, and Systems III
R. Rox Anderson, Editor(s)

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