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Proceedings Paper

Laser-assisted solder closure of bronchial stumps
Author(s): Mehmet Cengiz Oz; Matthew R. Williams; Richard D. Moscarelli; Murat Kaynar; Christian I. Fras; Steven K. Libutti; Hillary Smith; Adrianne J. Setton; Michael R. Treat; Roman Nowygrod
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Paper Abstract

Broncho-pleural fistula is a difficult clinical problem without a simple solution. Laser-assisted solder techniques potentially offer a means to precisely fix tissue glues into the fistulae through a bronchoscopic approach. Using a canine model, secondary bronchi were sealed with cryoprecipitate made from solvent/detergent treated plasma (treated to inactivate membrane enveloped virus) mixed with indocyanine green (absorption 805 nm). Diode laser energy (emission 808 nm, 7.3 W/cm2) was applied to the solder until desiccation was observed. Leakage pressures ranged between 18 - 86 mmHg with a mean of 46 +/- 24 mmHg. Laser-assisted solder techniques provide a reliably strong seal over leaking bronchial stumps and use of dye enhancement prevents undesired collateral thermal injury to surrounding bronchial tissue. Solvent/detergent plasma, prepared by methods shown to inactivate large quantities of HIV, HBV, and HCV, is an effective source of cyroprecipitate and should allow widespread use of pooled human material in a clinical setting.

Paper Details

Date Published: 1 June 1992
PDF: 4 pages
Proc. SPIE 1643, Laser Surgery: Advanced Characterization, Therapeutics, and Systems III, (1 June 1992); doi: 10.1117/12.137341
Show Author Affiliations
Mehmet Cengiz Oz, Columbia Univ. College of Physicians and Surgeons (United States)
Matthew R. Williams, Columbia Univ. College of Physicians and Surgeons (United States)
Richard D. Moscarelli, Columbia Univ. College of Physicians and Surgeons (United States)
Murat Kaynar, Columbia Univ. College of Physicians and Surgeons (United States)
Christian I. Fras, Columbia Univ. College of Physicians and Surgeons (United States)
Steven K. Libutti, Columbia Univ. College of Physicians and Surgeons (United States)
Hillary Smith, Columbia Univ. College of Physicians and Surgeons (United States)
Adrianne J. Setton, Columbia Univ. College of Physicians and Surgeons and New York Blood Ctr. (United States)
Michael R. Treat, Columbia Univ. College of Physicians and Surgeons (United States)
Roman Nowygrod, Columbia Univ. College of Physicians and Surgeons (United States)


Published in SPIE Proceedings Vol. 1643:
Laser Surgery: Advanced Characterization, Therapeutics, and Systems III
R. Rox Anderson, Editor(s)

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