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Proceedings Paper

Changes in optical density of vascular tissue after 308-nm excimer laser irradiation
Author(s): Hans-Joachim Schwarzmaier; Matthias P. Heintzen; Wolfram Mueller; Raimund Kaufmann; Myron Lee Wolbarsht
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Paper Abstract

Ninety-six transmission spectra were obtained from autopsy specimens of healthy human abdominal aorta. Specimens were irradiated via a 900 micrometers fused silica fiber (contact mode) under normal saline at room temperature (21.5 +/- 1.5 degree(s)C) using an excimer laser (308 nm, 40 Hz, 115 ns, 57 mJ/mm2). The temperature increased at the fiber tip up to 66.8 +/- 8.5 degree(s)C and was monitored by a NiCrNi thermocouple. Tissue samples from untreated areas and from the thermal damage zone next to the ablation area were anayzed by microspectrophotometry (spectral range 250-800 nm, cryosections 24 micrometers , area measured 6/3 (mu) in diameter). The conclusion is, excimer laser irradiation using a high repetition rate in combination with a high output energy changes the optical properties of human vessel walls significantly.

Paper Details

Date Published: 28 August 1992
PDF: 7 pages
Proc. SPIE 1642, Diagnostic and Therapeutic Cardiovascular Interventions II, (28 August 1992); doi: 10.1117/12.137295
Show Author Affiliations
Hans-Joachim Schwarzmaier, Heinrich-Heine Univ. (Germany)
Matthias P. Heintzen, Heinrich-Heine Univ. (Germany)
Wolfram Mueller, Heinrich-Heine Univ. (Germany)
Raimund Kaufmann, Heinrich-Heine Univ. (Germany)
Myron Lee Wolbarsht, Duke Univ. (United States)

Published in SPIE Proceedings Vol. 1642:
Diagnostic and Therapeutic Cardiovascular Interventions II
George S. Abela, Editor(s)

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