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Proceedings Paper

Photodynamic effects of Can-Sha photosensitizer on transplanted tumors in mice
Author(s): Jixiu Zhong; Lingling Zhu; Weijia Li; Yonghua Yang
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Paper Abstract

Can-sha photosensitizer (CPS) extracted from the silkworm excreta (a Chinese herb) was administered to tumor bearing mice by iv or the intragastrointestinal route in dosages of 50 mg/kg and 550 mg/kg, respectively. Six to ten hours later the tumorous site was irradiated with light. The results showed that the tumor inhibition rates were 69 - 98% by iv and 62 - 79% by intraduodenal (id) injection, but no photodynamic effect was found in the tumors of mice after administering CPD by p.o. 3H-TdR or 3-uR incorporation ability of the tumor cells pretreated with the drug and light was significantly inhibited.

Paper Details

Date Published: 5 March 1993
PDF: 3 pages
Proc. SPIE 1616, International Conference on Photodynamic Therapy and Laser Medicine, (5 March 1993); doi: 10.1117/12.137023
Show Author Affiliations
Jixiu Zhong, Zhejiang Academy of Traditional Chinese Medicine (China)
Lingling Zhu, Zhejiang Academy of Traditional Chinese Medicine (China)
Weijia Li, Zhejiang Academy of Traditional Chinese Medicine (China)
Yonghua Yang, Zhejiang Academy of Traditional Chinese Medicine (China)


Published in SPIE Proceedings Vol. 1616:
International Conference on Photodynamic Therapy and Laser Medicine
Junheng Li, Editor(s)

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