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Optical Engineering

Neuroscience Application Of Interactive Image Analysis
Author(s): Arthur W. Toga; Robert L. Goo; Robert Murphy; Robert C. Collins
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Paper Abstract

The goal of neuroscience is to understand how different parts of the brain are wired together and how they communicate with one another. Several recently developed techniques use a method known as autoradiography to create images of brain connectivity and function. These autoradiographic methods promise to be quantitative and comprehensive. HoweVer, the data appear as gray scale images, which presents certain data analysis problems. Through a collaborative effort between neuroscientists, engineers, and com-puter scientists, we have developed a computer-based quantitative image analysis system. We have designed an interactive menu-driven software pack-age. Our objective was to allow neuroscientists to quantitate, tabulate, and interpret the image data collected on autoradiographic files. A description of the hardware, the software package, and its application is presented.

Paper Details

Date Published: 1 June 1984
PDF: -278 pages
Opt. Eng. 23(3) doi: 10.1117/12.7973278
Published in: Optical Engineering Volume 23, Issue 3
Show Author Affiliations
Arthur W. Toga, Washington University School of Medicine (United States)
Robert L. Goo, Washington University School of Medicine (United States)
Robert Murphy, Washington University School of Medicine (United States)
Robert C. Collins, Washington University School of Medicine (United States)


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