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Optical Engineering

Automatic Recognition of White Blood Cells
Author(s): Robert S. Ledley; George C. Cheng
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Paper Abstract

APPROACH TO DIFFERENTIATING AMONG WHITE BLOOD CELLS A problem of great importance in medicine is that of distinguishing among different types of white blood cells, or leucocvtes. Unlike the red blood cell, the white blood cell has a nucleus. The nucleus may be round in shape â€" that is, can have a circular boundary as seen through the microscope - or it can be kidney-shaped, or it can have two, three, or more lobes, see Figure 1 a. The general theory is that a white blood cell starts out with a circular nucleus, which as the cell matures becomes kidney-shaped, and finally lobular, or Polymorphonuclear. Thus our problem becomes one of distinguishing among these shapes of nuclear boundaries.

Paper Details

Date Published: 1 September 1970
PDF: 4 pages
Opt. Eng. 8(6) doi: 10.1117/12.7971522
Published in: Optical Engineering Volume 8, Issue 6
Show Author Affiliations
Robert S. Ledley, National Biomedical Research Foundation (United States)
George C. Cheng, National Biomedical Research Foundation (United States)


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