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Optical Engineering

Coherent fiber optic sensor for early detection of cataractogenesis in a human eye lens
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Paper Abstract

A lensless backscatter fiber optic probe is used to measure the size distribution of protein molecules inside an excised, but intact, human eye lens. The fiber optic probe, about 5 mm in diameter, can be positioned arbitrarily close to the anterior surface of the eye; it is a transreceiver, which delivers a Gaussian laser beam into a small region inside the lens and provides a coherent detection of the laser light scattered by the protein molecules in the backward direction. Protein sizes determined from the fast and slow diffusion coefficients show good correlation with the age of the lens and cataractogenesis.

Paper Details

Date Published: 1 February 1993
PDF: 6 pages
Opt. Eng. 32(2) doi: 10.1117/12.60741
Published in: Optical Engineering Volume 32, Issue 2
Show Author Affiliations
Harbans S. Dhadwal, State Univ. of New York/Stony Brook (United States)
Rafat R. Ansari, NASA Lewis Research Ctr. (United States)
Michael A. DellaVecchia, Wills Eye Hospital (United States)

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