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Optical Engineering

Speckle fluctuations and biomedical optics: implications and applications
Author(s): J. David Briers
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Paper Abstract

Laser speckle limits the resolution that can be achieved in holography. Time-varying speckle, caused by scattering from moving objects, is even more troublesome. It can destroy the correlation needed to obtain fringes in holographic interferometry and even, ifthe fluctuations are rapid compared with the exposure time needed, the coherence needed to record a hologram. These problems are discussed, with particular reference to biomedical holography, and suggestions are made for minimizing their effect. Some positive aspects of time-varying speckle are also discussed. The fluctuations obey the same statistics as the spatial variations of a stationary speckle pattern. These statistics can be used to measure the movement of the scattering particles, a technique of particular value in biomedical science. Potential applications include monitoring blood flow, motility, and intracellular activity.

Paper Details

Date Published: 1 February 1993
PDF: 7 pages
Opt. Eng. 32(2) doi: 10.1117/12.60734
Published in: Optical Engineering Volume 32, Issue 2
Show Author Affiliations
J. David Briers, Kingston Univ. (United Kingdom)

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