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Journal of Biomedical Optics

Indocyanine green videoangiography using cooled charge-coupled devices in central serous choroidopathy
Author(s): Claudio Ciamberlini; Vittorio Guarnieri; Giuseppe Longobardi; Pasquale Poggi; M. C. Donati; G. Panzardi
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Paper Abstract

In order to evaluate the use of low level light (LLL) indocyanine green angiography in the diagnosis and treatment of central serous choroidopathy (CSC), a new system for LLL infrared videoangiography is described. The system was coupled with a standard fundus camera employing a low-power continuous light source. The system consists of a cooled charge-coupled device (CCD) camera and a third-generation image intensifier. The CCD camera investigates the pathologies of choroidal images with very good performance in terms of spatial resolution, dynamic range, and signal-to-noise ratio. The image intensifier carries out the choroidal angiography in real time. The results of 48 cases of CSC demonstrated the following ICGV features: focal RPE leakage; hyperfluorescent areas appearing in late phases and underlying the focal leakage or pigment epithelium detachment (PED); PED in the guise of early hyperfluorescent areas; delays in choroidal filling. The findings support the hypothesis that CSC originates in the choroid with localized hyperpermeability. The system described minimized retinal illumination and demonstrated increased angiographic resolution and contrast compared with conventional ICG angiographic systems.

Paper Details

Date Published: 1 April 1997
PDF: 8 pages
J. Biomed. Opt. 2(2) doi: 10.1117/12.268939
Published in: Journal of Biomedical Optics Volume 2, Issue 2
Show Author Affiliations
Claudio Ciamberlini, Istituto Nazionale di Ottica (Italy)
Vittorio Guarnieri, Istituto Nazionale di Ottica (Italy)
Giuseppe Longobardi, Istituto Nazionale di Ottica (Italy)
Pasquale Poggi, Istituto Nazionale di Ottica (Italy)
M. C. Donati, Univ. di Firenze (Italy)
G. Panzardi, Univ. di Firenze (Italy)


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