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Journal of Biomedical Optics

Neonatal intensive care: an obvious, yet difficult area for cerebral near-infrared spectroscopy
Author(s): Lotte Skov; Nikolai C. Brun; Gorm Greisen
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Paper Abstract

The first clinical application of near-infrared spectroscopy (NIRS) 11 years ago was on the head of newborn infants under intensive care. Since then much credible and some important data have been accumulated in this area of research. The best data have been obtained using manipulation of arterial oxygen saturation to obtain single or repeated estimates of cerebral blood flow or cerebral blood volume, or interference with cerebral venous return to obtain measures of venous oxygen saturation. It has been more difficult to take advantage of the continuous and noninvasive nature of NIRS. In particular, the value of the cytochrome signal can still be doubted. A role has not yet developed for NIRS in clinical neonatology.

Paper Details

Date Published: 1 January 1997
PDF: 8 pages
J. Biomed. Opt. 2(1) doi: 10.1117/12.260021
Published in: Journal of Biomedical Optics Volume 2, Issue 1
Show Author Affiliations
Lotte Skov, Rigshospitalet (Denmark)
Nikolai C. Brun, Rigshospitalet (Denmark)
Gorm Greisen, Rigshospitalet (Denmark)

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