Share Email Print
cover

Journal of Biomedical Optics

Low-frequency variability in the blood volume and in the blood volume pulse measured by photoplethysmography
Author(s): Meir Nitzan; Sergei Turivnenko; Adina Milston; Anatoly Babchenko; Y. Mahler
Format Member Price Non-Member Price
PDF $20.00 $25.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

Besides heart rate and arterial blood pressure, several parameters of the cardiovascular system fluctuate spontaneously. In the current study, the fluctuations of tissue blood content and blood volume pulse were investigated using two parameters of the photoplethysmographic (PPG) signal: the parameter BV, defined by: BV=Const−BL where BL is the baseline of the PPG signal, and the amplitude (AM), which are related to the blood volume and to the systolic blood volume increase, respectively. The PPG measurements were performed on the fingertips of ten healthy male subjects for 5 to 10 min and the PPG signal was digitally analyzed. Both BV and AM show low frequency fluctuations, which, for 23 out of 26 examinations, were positively correlated, with a lag of BV relative to AM. In three examinations, however, the two parameters were inversely correlated. A lower correlation was found between each of these parameters and the PPG period, which is actually the cardiac period. The results show that several mechanisms are involved in the spontaneous periodic fluctuations in the vascoconstriction level, which are known to be mediated by the sympathetic nervous system. The digital PPG provides, therefore, a potential tool for evaluating the role of the sympathetic nerves in the regulation of the microcirculation.

Paper Details

Date Published: 1 April 1996
PDF: 7 pages
J. Biomed. Opt. 1(2) doi: 10.1117/12.231366
Published in: Journal of Biomedical Optics Volume 1, Issue 2
Show Author Affiliations
Meir Nitzan, Jerusalem College of Technology (Israel)
Sergei Turivnenko, Jerusalem College of Technology (Israel)
Adina Milston, Jerusalem College of Technology (Israel)
Anatoly Babchenko, Jerusalem College of Technology (Israel)
Y. Mahler, Hadassah Univ. Hospital (Israel)


© SPIE. Terms of Use
Back to Top