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Optical Engineering

Highly integrated lab-on-a-chip for fluorescence detection
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Paper Abstract

We report the fabrication and validation of a microfluidic chip for fluorescence detection, which incorporates in the same glass substrate the microfluidic network, the excitation, the filtering, and the collection elements. The device is fabricated in a hybrid approach combining different technologies, such as femtosecond laser micromachining and RF sputtering, to increase their individual capabilities. The validation of the chip demonstrates a good wavelength selective light filtering and a limit of detection of a 600-nM concentration of Oxazine 720 perchlorate dye.

Paper Details

Date Published: 2 September 2016
PDF: 7 pages
Opt. Eng. 55(9) 097102 doi: 10.1117/1.OE.55.9.097102
Published in: Optical Engineering Volume 55, Issue 9
Show Author Affiliations
Surya S. K. Guduru, Istituto Italiano di Tecnologia (Italy)
Politecnico di Milano (Italy)
Francesco Scotognella, Politecnico di Milano (Italy)
Alessandro Chiasera, Istituto di Fotonica e Nanotecnologie, Consiglio Nazionale delle Ricerche, (Italy)
Valligatla Sreeramulu, CNR-IFN Padova (Italy)
Luigino Criante, Istituto Italiano di Tecnologia (Italy)
Krishna Chaitanya Vishnubhatla, Sri Sathya Sai Institute of Higher Learning (India)
Maurizio Ferrari, CNR-Istituto di Fotonica e Nanotecnologie (Italy)
Roberta Ramponi, CNR-Istituto di Fotonica e Nanotecnologie (Italy)
Guglielmo Lanzani, Istituto Italiano di Tecnologia (Italy)
Rebeca Martínez Vázquez, CNR-Istituto di Fotonica e Nanotecnologie (Italy)

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