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Neurophotonics • Open Access

Cerebral oximetry in preterm infants: an agenda for research with a clear clinical goal
Author(s): Gorm Greisen; Bjørn Andresen; Anne Mette Plomgaard; Simon Hyttel-Sørensen

Paper Abstract

Preterm birth constitutes a major cause of death before 5 years of age and it is a major cause of neurodevelopmental impairment across the world. Preterm infants are most unstable during the transition between fetal and newborn life during the first days of life and most brain damage occurs in this period. The brain of the preterm infant is accessible for tissue oximetry by near-infrared spectroscopy. Cerebral oximetry has the potential to improve the long-term outcome by helping to tailor the support of respiration and circulation to the individual infant’s needs, but the evidence is still lacking. The goals for research include testing the benefit and harms of cerebral oximetry in large-scale randomized trials, improved definition of the hypoxic threshold, better understanding the effects of intensive care on cerebral oxygenation, as well as improved precision of oximeters and calibration among devices or standardization of values in the hypoxic range. These goals can be pursued in parallel.

Paper Details

Date Published: 25 April 2016
PDF: 6 pages
3(3) 031407 doi: 10.1117/1.NPh.3.3.031407
Published in: Neurophotonics Volume 3, Issue 3
Show Author Affiliations
Gorm Greisen, Rigshospitalet (Denmark)
Bjørn Andresen, Rigshospitalet (Denmark)
Anne Mette Plomgaard, Rigshospitalet (Denmark)
Simon Hyttel-Sørensen, Rigshospitalet (Denmark)


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