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Neurophotonics • Open Access

Short-channel functional near-infrared spectroscopy regressions improve when source-detector separation is reduced
Author(s): James R. Goodwin; Chantel R. Gaudet; Andrew J. Berger

Paper Abstract

In functional near-infrared spectroscopy (fNIRS) of human cerebral hemodynamics, dedicated surface-sensitive recording channels are useful for regressing out background hemodynamics and isolating activation-specific responses. A wide variety of source-detector separations have been utilized for this purpose. Here, we report a direct comparison of regression performance between two extremes of the reported range, 13 and 6 mm. Measurements of visual stimulation response (flickering radial checkerboard) were obtained from nine adults using a standard commercial source-detector grid with 13-mm diagonals, into which three extra detector fibers were placed to provide 6-mm channels at certain locations. When the NIRS recordings (17 total trials) were processed, the contrast-to-noise ratio was significantly higher with 6-mm regression channels than with 13 mm. The advantage could be due in part to the undesired sensing of brain activity by the 13-mm channels. We suggest that shorter distances be considered for optimal removal of superficial hemodynamics in NIRS signals from the adult brain.

Paper Details

Date Published: 15 July 2014
PDF: 6 pages
Neurophoton. 1(1) 015002 doi: 10.1117/1.NPh.1.1.015002
Published in: Neurophotonics Volume 1, Issue 1
Show Author Affiliations
James R. Goodwin, Univ. of Rochester (United States)
Queensland Univ. of Technology (Australia)
Chantel R. Gaudet, Univ. of Rochester (United States)
Andrew J. Berger, Univ. of Rochester (United States)

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