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Journal of Nanophotonics

Plasmonic phototherapy using gold nanospheres and gold nanorods irradiated with light-emitting diodes
Author(s): Gananathan Poorani; Aruna Prakasa Rao; Ganesan Singaravelu; Elanchezhiyan Manickan
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Paper Abstract

Gold nanoparticles (GNPs) provide different modes of therapeutic responses in cells depending on their size and shape. We have studied two modifications of GNPs exhibiting surface plasmon resonances (SPRs) with phototherapeutic effects in nonmalignant Vero and malignant HeLa cell lines. The cells were treated with 30-nm-size gold nanospheres (GNSs) (having SPR at a wavelength of 530 nm) and with gold nanorods (GNRs) (having SPR at 630 nm). The plasmonic phototherapy effect in cells was provided by irradiating them with green and red light-emitting diodes (LEDs). The cytotoxicities of GNPs were determined by MTT assay. Both the GNSs and GNRs were found to be biocompatible and have efficient phototherapeutic activity with LEDs.

Paper Details

Date Published: 15 June 2016
PDF: 9 pages
J. Nanophoton. 10(2) 026027 doi: 10.1117/1.JNP.10.026027
Published in: Journal of Nanophotonics Volume 10, Issue 2
Show Author Affiliations
Gananathan Poorani, Anna Univ., Chennai (India)
Aruna Prakasa Rao, Anna Univ., Chennai (India)
Ganesan Singaravelu, Anna Univ., Chennai (India)
Elanchezhiyan Manickan, Univ. of Madras Taramani Campus (India)

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