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Journal of Medical Imaging

Preclinical imaging of iridocorneal angle and fundus using a modified integrated flexible handheld probe
Author(s): Xun Jie Jeesmond Hong; Vengalathunadakal K. Shinoj; Vadakke Matham Murukeshan; Mani Baskaran; Tin Aung
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Paper Abstract

A flexible handheld imaging probe consisting of a 3    mm × 3    mm charge-coupled device camera, light-emitting diode light sources, and near-infrared laser source is designed and developed. The imaging probe is designed with specifications to capture the iridocorneal angle images and posterior segment images. Light propagation from the anterior chamber of the eye to the exterior is considered analytically using Snell’s law. Imaging of the iridocorneal angle region and fundus is performed on ex vivo porcine samples and subsequently on small laboratory animals, such as the New Zealand white rabbit and nonhuman primate, in vivo. The integrated flexible handheld probe demonstrates high repeatability in iridocorneal angle and fundus documentation. The proposed concept and methodology are expected to find potential application in the diagnosis, prognosis, and management of glaucoma.

Paper Details

Date Published: 10 April 2017
PDF: 6 pages
J. Med. Imag. 4(2) 026001 doi: 10.1117/1.JMI.4.2.026001
Published in: Journal of Medical Imaging Volume 4, Issue 2
Show Author Affiliations
Xun Jie Jeesmond Hong, Nanyang Technological Univ. (Singapore)
Vengalathunadakal K. Shinoj, Nanyang Technological Univ. (Singapore)
Vadakke Matham Murukeshan, Nanyang Technological Univ. (Singapore)
Mani Baskaran, Singapore Eye Research Institute (Singapore)
Duke-NUS Graduae Medicine School (Singapore)
Singapore National Eye Centre (Singapore)
Tin Aung, Singapore Eye Research Institute (Singapore)
Duke-NUS Graduate Medicine School (Singapore)
National Univ. of Singapore (Singapore)

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