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Journal of Medical Imaging • Open Access

Task-based optimization of flip angle for fibrosis detection in T1-weighted MRI of liver
Author(s): Jonathan F. Brand; Lars R. Furenlid; Maria I. Altbach; Jean-Phillippe Galons; Achyut Bhattacharyya; Puneet Sharma; Tulshi Bhattacharyya; Ali Bilgin; Diego R. Martin

Paper Abstract

Chronic liver disease is a worldwide health problem, and hepatic fibrosis (HF) is one of the hallmarks of the disease. The current reference standard for diagnosing HF is biopsy followed by pathologist examination; however, this is limited by sampling error and carries a risk of complications. Pathology diagnosis of HF is based on textural change in the liver as a lobular collagen network that develops within portal triads. The scale of collagen lobules is characteristically in the order of 1 to 5 mm, which approximates the resolution limit of

Paper Details

Date Published: 21 July 2016
PDF: 9 pages
J. Med. Imag. 3(3) 035502 doi: 10.1117/1.JMI.3.3.035502
Published in: Journal of Medical Imaging Volume 3, Issue 3
Show Author Affiliations
Jonathan F. Brand, Univ. of Arizona (United States)
Lars R. Furenlid, Univ. of Arizona (United States)
Maria I. Altbach, Univ. of Arizona (United States)
Jean-Phillippe Galons, Univ. of Arizona (United States)
Achyut Bhattacharyya, Univ. of Arizona (United States)
Puneet Sharma, Univ. of Arizona (United States)
Tulshi Bhattacharyya, Univ. of Arizona (United States)
Ali Bilgin, Univ. of Arizona (United States)
Diego R. Martin, Univ. of Arizona College of Medicine (United States)


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