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Journal of Medical Imaging

Demonstration of synchrotron x-ray phase contrast imaging computed tomography of infiltrative transitional cell carcinoma of the prostatic urethra in a dog
Author(s): James E. Montgomery; Michael J. Wesolowski; Bailey Wolkowski; Rajni Chibbar; Elisabeth C. R. Snead; Jaswant Singh; Murray Pettitt; Pritpal S. Malhi; Trinita Barboza; Gregg Adams
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Paper Abstract

Prostatic urethral transitional cell carcinoma with prostatic invasion in a dog was imaged with abdominal radiography and abdominal ultrasonography antemortem. Synchrotron in-line x-ray phase contrast imaging computed tomography (XPCI-CT) was performed on the prostate <italic<ex vivo</italic< at the Canadian Light Source Synchrotron and compared to histology. XPCI-CT imaging provides greater soft tissue contrast than conventional absorption-based x-ray imaging modalities, permitting visualization of regions of inflammatory cell infiltration, differentiation of invasive versus noninvasive tumor regions, and areas of necrosis and mineralization. This represents the first report of XPCI-CT images of an invasive prostatic urothelial neoplasm in a dog.

Paper Details

Date Published: 14 March 2016
PDF: 7 pages
J. Med. Img. 3(1) 015504 doi: 10.1117/1.JMI.3.1.015504
Published in: Journal of Medical Imaging Volume 3, Issue 1
Show Author Affiliations
James E. Montgomery, Univ. of Saskatchewan (Canada)
Michael J. Wesolowski, Univ. of Saskatchewan (Canada)
Bailey Wolkowski, Univ. of Saskatchewan (Canada)
Rajni Chibbar, Univ. of Saskatchewan (Canada)
Elisabeth C. R. Snead, Univ. of Saskatchewan (Canada)
Jaswant Singh, Univ. of Saskatchewan (Canada)
Murray Pettitt, Univ. of Saskatchewan (Canada)
Pritpal S. Malhi, Univ. of Saskatchewan (Canada)
Trinita Barboza, Univ. of Saskatchewan (Canada)
Gregg Adams, Univ. of Saskatchewan (Canada)

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