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Journal of Medical Imaging

Improved image reconstruction of low-resolution multichannel phase contrast angiography
Author(s): Akshara P. Krishnan; Ajin Joy; Joseph Suresh Paul
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Paper Abstract

In low-resolution phase contrast magnetic resonance angiography, the maximum intensity projected channel images will be blurred with consequent loss of vascular details. The channel images are enhanced using a stabilized deblurring filter, applied to each channel prior to combining the individual channel images. The stabilized deblurring is obtained by the addition of a nonlocal regularization term to the reverse heat equation, referred to as nonlocally stabilized reverse diffusion filter. Unlike reverse diffusion filter, which is highly unstable and blows up noise, nonlocal stabilization enhances intensity projected parallel images uniformly. Application to multichannel vessel enhancement is illustrated using both volunteer data and simulated multichannel angiograms. Robustness of the filter applied to volunteer datasets is shown using statistically validated improvement in flow quantification. Improved performance in terms of preserving vascular structures and phased array reconstruction in both simulated and real data is demonstrated using structureness measure and contrast ratio.

Paper Details

Date Published: 22 January 2016
PDF: 11 pages
J. Med. Img. 3(1) 014001 doi: 10.1117/1.JMI.3.1.014001
Published in: Journal of Medical Imaging Volume 3, Issue 1
Show Author Affiliations
Akshara P. Krishnan, Indian Institute of Information Technology and Management-Kerala (India)
Ajin Joy, Indian Institute of Information Technology and Management-Kerala (India)
Joseph Suresh Paul, Indian Institute of Information Technology and Management-Kerala (India)


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