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Journal of Biomedical Optics • new

Wide-field absolute transverse blood flow velocity mapping in vessel centerline
Author(s): Nanshou Wu; Lei Wang; Bifeng Zhu; Caizhong Guan; Mingyi Wang; Dingan Han; Haishu Tan; Yaguang Zeng
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Paper Abstract

We propose a wide-field absolute transverse blood flow velocity measurement method in vessel centerline based on absorption intensity fluctuation modulation effect. The difference between the light absorption capacities of red blood cells and background tissue under low-coherence illumination is utilized to realize the instantaneous and average wide-field optical angiography images. The absolute fuzzy connection algorithm is used for vessel centerline extraction from the average wide-field optical angiography. The absolute transverse velocity in the vessel centerline is then measured by a cross-correlation analysis according to instantaneous modulation depth signal. The proposed method promises to contribute to the treatment of diseases, such as those related to anemia or thrombosis.

Paper Details

Date Published: 27 February 2018
PDF: 7 pages
J. Biomed. Opt. 23(2) 026008 doi: 10.1117/1.JBO.23.2.026008
Published in: Journal of Biomedical Optics Volume 23, Issue 2
Show Author Affiliations
Nanshou Wu, Foshan Univ. (China)
Lei Wang, Foshan Univ. (China)
Bifeng Zhu, Foshan Univ. (China)
Caizhong Guan, Foshan University, Department of Physics and Optoelectronic Engineering, Guangdong (China)
Mingyi Wang, Foshan Univ. (China)
Dingan Han, Foshan Univ. (China)
Haishu Tan, Foshan Univ. (China)
Yaguang Zeng, Foshan Univ. (China)

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