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Journal of Biomedical Optics

Enhanced linear-array photoacoustic beamforming using modified coherence factor
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Paper Abstract

Photoacoustic imaging (PAI) is a promising medical imaging modality providing the spatial resolution of ultrasound imaging and the contrast of optical imaging. For linear-array PAI, a beamformer can be used as the reconstruction algorithm. Delay-and-sum (DAS) is the most prevalent beamforming algorithm in PAI. However, using DAS beamformer leads to low-resolution images as well as high sidelobes due to nondesired contribution of off-axis signals. Coherence factor (CF) is a weighting method in which each pixel of the reconstructed image is weighted, based on the spatial spectrum of the aperture, to mainly improve the contrast. We demonstrate that the numerator of the formula of CF contains a DAS algebra and propose the use of a delay-multiply-and-sum beamformer instead of the available DAS on the numerator. The proposed weighting technique, modified CF (MCF), has been evaluated numerically and experimentally compared to CF. It was shown that MCF leads to lower sidelobes and better detectable targets. The quantitative results of the experiment (using wire targets) show that MCF leads to for about 45% and 40% improvement, in comparison with CF, in the terms of signal-to-noise ratio and full-width-half-maximum, respectively.

Paper Details

Date Published: 14 February 2018
PDF: 10 pages
J. Biomed. Opt. 23(2) 026005 doi: 10.1117/1.JBO.23.2.026005
Published in: Journal of Biomedical Optics Volume 23, Issue 2
Show Author Affiliations
Moein Mozaffarzadeh, Research Ctr. for Biomedical Technologies and Robotics, Institute for Advanced Medical Technologies (Iran)
Tarbiat Modares Univ. (Iran)
Yan Yan, Wayne State Univ. (United States)
Mohammad Mehrmohammadi, Wayne State Univ. (United States)
Bahador Makkiabadi, Research Ctr. for Biomedical Technologies and Robotics, Institute for Advanced Medical Technologies (Iran, Islamic Republic of)
Tehran Univ. of Medical Sciences (Iran, Islamic Republic of)


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