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Journal of Biomedical Optics • Open Access

Tissue perfusion rate estimation with compression-based photoacoustic-ultrasound imaging
Author(s): Min Choi; A.M. James Shapiro; Roger Zemp

Paper Abstract

Tissue perfusion is essential for transporting blood oxygen and nutrients. Measurement of tissue perfusion rate would have a significant impact in clinical and preclinical arenas. However, there are few techniques to image this important parameter and they typically require contrast agents. A label-free methodology based on tissue compression and imaging with a high-frequency photoacoustic-ultrasound system is introduced for estimating and visualizing tissue perfusion rates. Experiments demonstrate statistically significant differences in depth-resolved perfusion rates in a human subject with various temperature exposure conditions.

Paper Details

Date Published: 18 January 2018
PDF: 7 pages
J. Biomed. Opt. 23(1) 016010 doi: 10.1117/1.JBO.23.1.016010
Published in: Journal of Biomedical Optics Volume 23, Issue 1
Show Author Affiliations
Min Choi, Univ. of Alberta (Canada)
A.M. James Shapiro, Univ. of Alberta (Canada)
Roger Zemp, Univ. of Alberta (Canada)


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