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Journal of Biomedical Optics • Open Access • new

Estimation of cerebral metabolic rate of oxygen consumption using combined multiwavelength photoacoustic microscopy and Doppler microultrasound
Author(s): Yan Jiang; Roger Zemp

Paper Abstract

The metabolic rate of oxygen consumption is an important metric of tissue oxygen metabolism and is especially critical in the brain, yet few methods are available for measuring it. We use a custom combined photoacoustic-microultrasound system and demonstrate cerebral oxygen consumption estimation in vivo. In particular, the cerebral metabolic rate of oxygen consumption was estimated in a murine model during variation of inhaled oxygen from hypoxia to hyperoxia. The hypothesis of brain autoregulation was confirmed with our method even though oxygen saturation and flow in vessels changed.

Paper Details

Date Published: 18 January 2018
PDF: 7 pages
J. Biomed. Opt. 23(1) 016009 doi: 10.1117/1.JBO.23.1.016009
Published in: Journal of Biomedical Optics Volume 23, Issue 1
Show Author Affiliations
Yan Jiang, Univ. of Alberta (Canada)
Roger Zemp, Univ. of Alberta (Canada)

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